Physiologische Chemie Tiermedizin




Publications 2018

Fluorinated Carbohydrates as Lectin Ligands: Synthesis of OH/F-Substituted N-Glycan Core Trimannoside and Epitope Mapping by 2D STD-TOCSYreF NMR spectroscopy.
Diercks T, Infantino AS, Unione L, Jiménez-Barbero J, Oscarson S, Gabius H-J.
Chemistry. 2018 Oct 22;24(59):15761-15765.

Galectin-4, a Negative Regulator of Oligodendrocyte Differentiation, Is Persistently Present in Axons and Microglia/Macrophages in Multiple Sclerosis Lesions.
de Jong CGHM, Stancic M, Pinxterhuis TH, van Horssen J, van Dam AM, Gabius H-J, Baron W. J
Neuropathol Exp Neurol. 2018 Nov 1;77(11):1024-1038.

Localization of Galectins within Glycocalyx.
Rapoport EM, Matveeva VK, Vokhmyanina OA, Belyanchikov IM, Gabius H-J, Bovin NV.
Biochemistry (Mosc). 2018 Jun;83(6):727-737.

Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail.
Flores-Ibarra A, Vértesy S, Medrano FJ, Gabius H-J, Romero A.
Sci Rep. 2018 Jun 29;8(1):9835.

Galectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.
Weinmann D, Kenn M, Schmidt S, Schmidt K, Walzer SM, Kubista B, Windhager R, Schreiner W, Toegel S, Gabius H-J.
Cell Mol Life Sci. 2018 Nov;75(22):4187-4205.

Glycan Chains of Gangliosides: Functional Ligands for Tissue Lectins (Siglecs/Galectins).
Ledeen RW, Kopitz J, Abad-Rodríguez J, Gabius H-J.
Prog Mol Biol Transl Sci. 2018;156:289-324.

From glycophenotyping by (plant) lectin histochemistry to defining functionality of glycans by pairing with endogenous lectins.
Kaltner H, García Caballero G, Ludwig AK, Manning JC, Gabius H-J.
Histochem Cell Biol. 2018 Jun;149(6):547-568.

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.
Orozco CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, Dalotto-Moreno T, Iglesias M, Moreno M, Djurec M, Poirier F, Gabius H-J, Fernandez-Zapico ME, Hwang RF, Guerra C, Rabinovich GA, Navarro P.
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3769-E3778.

Three-step monitoring of glycan and galectin profiles in the anterior segment of the adult chicken eye.
Manning JC, García Caballero G, Knospe C, Kaltner H, Gabius H-J.
Ann Anat. 2018 May;217:66-81.

Detection of Distinct Changes in Gene-expression Profiles in Specimens of Tumors and Transition Zones of Tenascin-positive/-negative Head and Neck Squamous Cell Carcinoma.
Zivicova V, Gal P, Mifkova A, Novak S, Kaltner H, Kolar M, Strnad H, Sachova J, Hradilova M, Chovanec M, Gabius H-J, Smetana K Jr, Fik Z.
Anticancer Res. 2018 Mar;38(3):1279-1290.

Exploring functional pairing between surface glycoconjugates and human galectins using programmable glycodendrimersomes.
Xiao Q, Ludwig AK, Romanò C, Buzzacchera I, Sherman SE, Vetro M, Vértesy S, Kaltner H, Reed EH, Möller M, Wilson CJ, Hammer DA, Oscarson S, Klein ML, Gabius H-J, Percec V.
Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2509-E2518.

Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers.
Miller MC, Ludwig AK, Wichapong K, Kaltner H, Kopitz J, Gabius H-J, Mayo KH.
Biochem J. 2018 Mar 15;475(5):1003-1018.

Chicken GRIFIN: Structural characterization in crystals and in solution.
Ruiz FM, Gilles U, Ludwig AK, Sehad C, Shiao TC, García Caballero G, Kaltner H, Lindner I, Roy R, Reusch D, Romero A, Gabius H-J.
Biochimie. 2018 Mar;146:127-138.

The sugar code: Why glycans are so important.
Gabius H-J.
Biosystems. 2018 Feb;164:102-111.