Physiologische Chemie Tiermedizin




Publications 2017

How to Crack the Sugar Code.
Gabius H-J.
Folia Biol (Praha). 2017;63(4):121-131.

Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.
Katzenmaier EM, Kloor M, Gabius H-J, Gebert J, Kopitz J.
IUBMB Life. 2017 Dec;69(12):962-970.

Neurons define non-myelinated axon segments by the regulation of galectin-4-containing axon membrane domains.
Díez-Revuelta N, Higuero AM, Velasco S, Peñas-de-la-Iglesia M, Gabius H-J, Abad-Rodríguez J.
Sci Rep. 2017 Sep 25;7(1):12246.

Combination of galectin-3, CK19 and HBME-1 immunostaining improves the diagnosis of thyroid cancer.
Arcolia V, Journe F, Renaud F, Leteurtre E, Gabius H-J, Remmelink M, Saussez S.
Oncol Lett. 2017 Oct;14(4):4183-4189

Reaction of a Programmable Glycan Presentation of Glycodendrimersomes and Cells with Engineered Human Lectins To Show the Sugar Functionality of the Cell Surface.
Kopitz J, Xiao Q, Ludwig AK, Romero A, Michalak M, Sherman SE, Zhou X, Dazen C, Vértesy S, Kaltner H, Klein ML, Gabius H-J, Percec V.
Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14677-14681

Studying the Structural Significance of Galectin Design by Playing a Modular Puzzle: Homodimer Generation from Human Tandem-Repeat-Type (Heterodimeric) Galectin-8 by Domain Shuffling.
Ludwig AK, Michalak M, Shilova N, André S, Kaltner H, Bovin NV, Kopitz J, Gabius H-J.
Molecules. 2017 Sep 19;22(9). pii: E1572. doi: 10.3390/molecules22091572.

Galectin-1 is a diagnostic marker involved in thyroid cancer progression.
Arcolia V, Journe F, Wattier A, Leteurtre E, Renaud F, Gabius H-J, Remmelink M, Decaestecker C, Rodriguez A, Boutry S, Laurent S, Saussez S.
Int J Oncol. 2017 Sep;51(3):760-770

Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance.
Kaltner H, Szabó T, Fehér K, André S, Balla S, Manning JC, Szilágyi L, Gabius H-J.
Bioorg Med Chem. 2017 Jun 15;25(12):3158-3170.

Genome-wide Expression Profiling (with Focus on the Galectin Network) in Tumor, Transition Zone and Normal Tissue of Head and Neck Cancer: Marked Differences Between Individual Patients and the Site of Specimen Origin.
Zivicova V, Broz P, Fik Z, Mifkova A, Plzak J, Cada Z, Kaltner H, Kucerova JF, Gabius H-J, Smetana K Jr.
Anticancer Res. 2017 May;37(5):2275-2288.

Network analysis of adhesion/growth-regulatory galectins and their binding sites in adult chicken retina and choroid.
Manning JC, García Caballero G, Knospe C, Kaltner H, Gabius H-J.
J Anat. 2017 Jul;231(1):23-37.

Long-chain GM1 gangliosides alter transmembrane domain registration through interdigitation.
Manna M, Javanainen M, Monne HM, Gabius H-J, Rog T, Vattulainen I.
Biochim Biophys Acta. 2017 May;1859(5):870-878.

Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity.
Bayón C, He N, Deir-Kaspar M, Blasco P, André S, Gabius HJ, Rumbero Á, Jiménez-Barbero J, Fessner WD, Hernáiz MJ.
Chemistry. 2017 Jan 31;23(7):1623-1633.

Lectins: a primer for histochemists and cell biologists.
Manning JC, Romero A, Habermann FA, García Caballero G, Kaltner H, Gabius H-J.
Histochem Cell Biol. 2017 Feb;147(2):199-222.

Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.
Roy R, Cao Y, Kaltner H, Kottari N, Shiao TC, Belkhadem K, André S, Manning JC, Murphy PV, Gabius H-J.
Histochem Cell Biol. 2017 Feb;147(2):285-301.

Galectins: their network and roles in immunity/tumor growth control.
Kaltner H, Toegel S, Caballero GG, Manning JC, Ledeen RW, Gabius H-J.
Histochem Cell Biol. 2017 Feb;147(2):239-256.

An introduction to the sugar code.
Gabius H-J, Roth J.
Histochem Cell Biol. 2017 Feb;147(2):111-117.

Synthetic Mucin-Like Glycopeptides as Versatile Tools to Measure Effects of Glycan Structure/Density/Position on the Interaction with Adhesion/Growth-Regulatory Galectins in Arrays.
Artigas G, Hinou H, Garcia-Martin F, Gabius H-J, Nishimura SI.
Chem Asian J. 2017 Jan 3;12(1):159-167.