Physiologische Chemie Tiermedizin




Publications 2014

Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor-Associated Mucin Glycopeptides by the Human Macrophage Galactose-Type Lectin.
Marcelo F, Garcia-Martin F, Matsushita T, Sardinha J, Coelho H, Oude-Vrielink A, Koller C, André S, Cabrita EJ, Gabius HJ, Nishimura SI, Jiménez-Barbero J, Cañada FJ.
Chemistry. 2014 Oct 16.

Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro.
Katzenmaier EM, André S, Kopitz J, Gabius HJ.
Anticancer Res. 2014 Oct;34(10):5429-38.

Extracellular matrix of galectin-1-exposed dermal and tumor-associated fibroblasts favors growth of human umbilical vein endothelial cells in vitro: a short report.
Peržeľová V, Varinská L, Dvořánková B, Szabo P, Spurný P, Valach J, Mojžiš J, André S, Gabius HJ, Smetana K Jr, Gál P.
Anticancer Res. 2014 Aug;34(8):3991-6.

Rho GTPase Rac1: molecular switch within the galectin network and for N-glycan α2,6-sialylation/O-glycan core 1 sialylation in colon cancer in vitro.
André S, Singh T, Lacal JC, Smetana K Jr, Gabius HJ.
Folia Biol (Praha). 2014;60(3):95-107.

Human osteoarthritic knee cartilage: fingerprinting of adhesion/growth-regulatory galectins in vitro and in situ indicates differential upregulation in severe degeneration.
Toegel S, Bieder D, André S, Kayser K, Walzer SM, Hobusch G, Windhager R, Gabius HJ.
Histochem Cell Biol. 2014 Oct;142(4):373-88

Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer.
Richard V, Kindt N, Decaestecker C, Gabius HJ, Laurent G, Noël JC, Saussez S.
Oncol Rep. 2014 Aug;32(2):523-9

Mimicking biological membranes with programmable glycan ligands self-assembled from amphiphilic Janus glycodendrimers.
Zhang S, Moussodia RO, Sun HJ, Leowanawat P, Muncan A, Nusbaum CD, Chelling KM, Heiney PA, Klein ML, André S, Roy R, Gabius HJ, Percec V.
Angew Chem Int Ed Engl. 2014 Oct 6;53(41):10899-903

Human chimera-type galectin-3: defining the critical tail length for high-affinity glycoprotein/cell surface binding and functional competition with galectin-1 in neuroblastoma cell growth regulation.
Kopitz J, Vértesy S, André S, Fiedler S, Schnölzer M, Gabius HJ.
Biochimie. 2014 Sep;104:90-9.

Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro.
Mifková A, Kodet O, Szabo P, Kučera J, Dvořánková B, André S, Koripelly G, Gabius HJ, Lehn JM, Smetana K Jr.
Chembiochem. 2014 Jul 7;15(10):1465-70.

Galectin fingerprinting in naso-sinusal diseases.
Duray A, De Maesschalck T, Decaestecker C, Remmelink M, Chantrain G, Neiveyans J, Horoi M, Leroy X, Gabius HJ, Saussez S.
Oncol Rep. 2014 Jul;32(1):23-32

Lanthanide-chelating carbohydrate conjugates are useful tools to characterize carbohydrate conformation in solution and sensitive sensors to detect carbohydrate-protein interactions.
Canales Á, Mallagaray Á, Berbís MÁ, Navarro-Vázquez A, Domínguez G, Cañada FJ, André S, Gabius HJ, Pérez-Castells J, Jiménez-Barbero J.
J Am Chem Soc. 2014 Jun 4;136(22):8011-7.

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.
Martínez-Bosch N, Fernández-Barrena MG, Moreno M, Ortiz-Zapater E, Munné-Collado J, Iglesias M, André S, Gabius HJ, Hwang RF, Poirier F, Navas C, Guerra C, Fernández-Zapico ME, Navarro P.
Cancer Res. 2014 Jul 1;74(13):3512-24.

Combining glycocluster synthesis with protein engineering: an approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4).
André S, Wang GN, Gabius HJ, Murphy PV.
Carbohydr Res. 2014 May 7;389:25-38.

Introduction to glycopathology: the concept, the tools and the perspectives.
Gabius HJ, Kayser K.
Diagn Pathol. 2014 Jan 20;9:4.

Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells.
Ruiz FM, Scholz BA, Buzamet E, Kopitz J, André S, Menéndez M, Romero A, Solís D, Gabius HJ.
FEBS J. 2014 Mar;281(5):1446-64.

Towards Dissecting Molecular Routes of Intercellular Communication in the Tumour Microenvironment: Phenotypic Plasticity of Stem Cell-Associated Markers in Co-culture (Carcinoma Cell/Fibroblast) Systems.
Fík Z, Dvořánková B, Kodet O, Bouček J, Betka JA, Betka J, André S, Gabius HJ, Šnajdr P, Smetana K Jr, Chovanec M.
Folia Biol (Praha). 2014;60(5):205-12.

Phosphorylation of multifunctional galectins by protein kinases CK1, CK2, and PKA.
Kübler D, Seidler J, André S, Kumar S, Schwartz-Albiez R, Lehmann WD, Gabius HJ.
Anal Biochem. 2014 Mar 15;449:109-17.

Peptides derived from human galectin-3 N-terminal tail interact with its carbohydrate recognition domain in a phosphorylation-dependent manner.
Berbís MÁ, André S, Cañada FJ, Pipkorn R, Ippel H, Mayo KH, Kübler D, Gabius HJ, Jiménez-Barbero J.
Biochem Biophys Res Commun. 2014 Jan 3;443(1):126-31.

Human tandem-repeat-type galectins bind bacterial non-βGal polysaccharides.
Knirel YA, Gabius HJ, Blixt O, Rapoport EM, Khasbiullina NR, Shilova NV, Bovin NV.
Glycoconj J. 2014 Jan;31(1):7-12