Physiologische Chemie Tiermedizin




Publications 2012

Analysis of homodimeric avian and human galectins by two methods based on fluorescence spectroscopy: Different structural alterations upon oxidation and ligand binding.
Göhler A, Büchner C, André S, Sören Doose, Kaltner H, Gabius HJ.
Biochimie. 2012 Dec;94(12):2649-55.

Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses.
Kolář M, Szabo P, Dvořánková B, Lacina L, Gabius HJ, Strnad H, Sáchová J, Vlček C, Plzák J, Chovanec M, Cada Z, Betka J, Fík Z, Pačes J, Kovářová H, Motlík J, Jarkovská K, Smetana K Jr.
Biol Cell. 2012 Dec;104(12):738-51.

Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: increased expression of galectin-1 and induction of poor prognosis factors.
Valach J, Fík Z, Strnad H, Chovanec M, Plzák J, Cada Z, Szabo P, Sáchová J, Hroudová M, Urbanová M, Steffl M, Pačes J, Mazánek J, Vlček C, Betka J, Kaltner H, André S, Gabius HJ, Kodet R, Smetana K Jr, Gál P, Kolář M.
Int J Cancer. 2012 Dec 1;131(11):2499-508.

Studies related to norway spruce galactoglucomannans: chemical synthesis, conformation analysis, NMR spectroscopic characterization, and molecular recognition of model compounds.
Ekholm FS, Ardá A, Eklund P, André S, Gabius HJ, Jiménez-Barbero J, Leino R.
Chemistry. 2012 Nov 5;18(45):14392-405.

Galectin-3 binds Neisseria meningitidis and increases interaction with phagocytic cells.
Quattroni P, Li Y, Lucchesi D, Lucas S, Hood DW, Herrmann M, Gabius HJ, Tang CM, Exley RM.
Cell Microbiol. 2012 Nov;14(11):1657-75.

Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
Amano M, Eriksson H, Manning JC, Detjen KM, André S, Nishimura S, Lehtiö J, Gabius HJ.
FEBS J. 2012 Nov;279(21):4062-80.

Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro, immunohistochemical and transcriptomic analyses.
Kolář M, Szabo P, Dvořánková B, Lacina L, Gabius HJ, Strnad H, Sáchová J, Vlček C, Plzák J, Chovanec M, Cada Z, Betka J, Fík Z, Pačes J, Kovářová H, Motlík J, Jarkovská K, Smetana K Jr.
Biol Cell. 2012 Oct 9.

Expression of macrophage migration-inhibitory factor is correlated with progression in oral cavity carcinomas.
Kindt N, Lechien J, Decaestecker C, Rodriguez A, Chantrain G, Remmelink M, Laurent G, Gabius HJ, Saussez S.
Anticancer Res. 2012 Oct;32(10):4499-505.

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population.
Pál Z, Antal P, Srivastava SK, Hullám G, Semsei AF, Gál J, Svébis M, Soós G, Szalai C, André S, Gordeeva E, Nagy G, Kaltner H, Bovin NV, Molnár MJ, Falus A, Gabius HJ, Buzás EI.
Biochim Biophys Acta. 2012 Oct;1820(10):1512-8.

1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 31 kDa human galectin-7 (p53-induced gene 1) homodimer, a pro-apoptotic lectin.
Nesmelova IV, Berbís MÁ, Miller MC, Cañada FJ, André S, Jiménez-Barbero J, Gabius HJ, Mayo KH.
Biomol NMR Assign. 2012 Oct;6(2):127-9.

Molecular recognition of the Thomsen-Friedenreich antigen-threonine conjugate by adhesion/growth regulatory galectin-3: nuclear magnetic resonance studies and molecular dynamics simulations.
Yongye AB, Calle L, Ardá A, Jiménez-Barbero J, André S, Gabius HJ, Martínez-Mayorga K, Cudic M.
Biochemistry. 2012 Sep 18;51(37):7278-89. doi: 10.1021/bi300761s.

Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity.
Wang GN, André S, Gabius HJ, Murphy PV.
Org Biomol Chem. 2012 Sep 14;10(34):6893-907.

Comparative study of the glycan specificities of cell-bound human tandem-repeat-type galectin-4, -8 and -9.
Vokhmyanina OA, Rapoport EM, André S, Severov VV, Ryzhov I, Pazynina GV, Korchagina E, Gabius HJ, Bovin NV. Glycobiology. 2012 Sep;22(9):1207-17.

α-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands.
Marcelo F, Cañada FJ, André S, Colombo C, Doro F, Gabius HJ, Bernardi A, Jiménez-Barbero J.
Org Biomol Chem. 2012 Aug 14;10(30):5916-23.

Adhesion/growth-regulatory galectins in the human eye: localization profiles and tissue reactivities as a standard to detect disease-associated alterations.
Schlötzer-Schrehardt U, André S, Janko C, Kaltner H, Kopitz J, Gabius HJ, Herrmann M.
Graefes Arch Clin Exp Ophthalmol. 2012 Aug;250(8):1169-80.

Colonic carcinogenesis along different genetic routes: glycophenotyping of tumor cases separated by microsatellite instability/stability.
Gebert J, Kloor M, Lee J, Lohr M, André S, Wagner R, Kopitz J, Gabius HJ.
Histochem Cell Biol. 2012 Aug;138(2):339-50.

Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected].
Ledeen RW, Wu G, André S, Bleich D, Huet G, Kaltner H, Kopitz J, Gabius HJ.
Ann N Y Acad Sci. 2012 Apr;1253:206-21.

Atropa belladonna L. water extract: modulator of extracellular matrix formation in vitro and in vivo.
Gál P, Vasilenko T, Kováč I, Kostelníková M, Jakubčo J, Szabo P, Dvořánková B, Sabol F, Gabius HJ, Smetana K Jr.
Physiol Res. 2012 Jul 20;61(3):241-50.

Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome.
Janko C, André S, Munoz LE, Briand JP, Schorn C, Winkler S, Schiller M, Andreoli L, Manfredi AA, Isenberg DA, Schett G, Gabius HJ, Muller S, Herrmann M.
Lupus. 2012 Jun;21(7):781-3.

Ganglioside GM1/galectin-dependent growth regulation in human neuroblastoma cells: special properties of bivalent galectin-4 and significance of linker length for ligand selection.
Kopitz J, Ballikaya S, André S, Gabius HJ.
Neurochem Res. 2012 Jun;37(6):1267-76.

Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas.
Fík Z, Valach J, Chovanec M, Mazánek J, Kodet R, Kodet O, Tachezy R, Foltynová E, André S, Kaltner H, Gabius HJ, Smetana K Jr.
J Oral Pathol Med. 2012 May 31.

Down-regulation of the epidermal growth factor receptor by altering N-glycosylation: emerging role of β1,4-galactosyltransferases.
Gabius HJ, van de Wouwer M, André S, Villalobo A.
Anticancer Res. 2012 May;32(5):1565-72.

Galectin-4, a novel neuronal regulator of myelination.
Stancic M, Slijepcevic D, Nomden A, Vos MJ, de Jonge JC, Sikkema AH, Gabius HJ, Hoekstra D, Baron W.
Glia. 2012 May;60(6):919-35.

A toolbox of lectins for translating the sugar code: the galectin network in phylogenesis and tumors.
Kaltner H, Gabius HJ.
Histol Histopathol. 2012 Apr;27(4):397-416. Review.

Galectin fingerprinting detects differences in expression profiles between bovine endometrium and placentomes as well as early and late gestational stages.
Froehlich R, Hambruch N, Haeger JD, Dilly M, Kaltner H, Gabius HJ, Pfarrer C.
Placenta. 2012 Mar;33(3):195-201.

Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.
André S, Jarikote DV, Yan D, Vincenz L, Wang GN, Kaltner H, Murphy PV, Gabius HJ.
Bioorg Med Chem Lett. 2012 Jan 1;22(1):313-8.

Early stages of trachea healing process: (immuno/lectin) histochemical monitoring of selected markers and adhesion/growth-regulatory endogenous lectins.
Grendel T, Sokolský J, Vaščáková A, Hudák V, Chovanec M, Sabol F, André S, Kaltner H, Gabius HJ, Frankovičová M, Lenčeš P, Betka J, Smetana K Jr, Gál P.
Folia Biol (Praha). 2012;58(4):135-43.