Physiologische Chemie Tiermedizin




Publications 2011

Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy.
Göhler A, Büchner C, André S, Doose S, Kaltner H, Gabius HJ.
Analyst. 2011 Dec 21;136(24):5270-6

Structural aspects of binding of α-linked digalactosides to human galectin-1.
Miller MC, Ribeiro JP, Roldós V, Martín-Santamaría S, Cañada FJ, Nesmelova IA, André S, Pang M, Klyosov AA, Baum LG, Jiménez-Barbero J, Gabius HJ, Mayo KH.
Glycobiology. 2011 Dec;21(12):1627-41

Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.
André S, Jarikote DV, Yan D, Vincenz L, Wang GN, Kaltner H, Murphy PV, Gabius HJ.
Bioorg Med Chem Lett. 2011 Nov 10

Open Wound Healing In Vivo: Monitoring Binding and Presence of Adhesion/Growth-Regulatory Galectins in Rat Skin during the Course of Complete Re-Epithelialization.
Gál P, Vasilenko T, Kostelníková M, Jakubco J, Kovác I, Sabol F, André S, Kaltner H, Gabius HJ, Smetana K Jr.
Acta Histochem Cytochem. 2011 Oct 26;44(5):191-9

Carbohydrate specificity of chicken and human tandem-repeat-type galectins-8 in composition of cells.
Vokhmyanina OA, Rapoport EM, Ryzhov IM, Korchagina EY, Pazynina GV, Severov VV, Kaltner H, André S, Gabius HJ, Bovin NV.
Biochemistry (Mosc). 2011 Oct;76(10):1185-92

Increased expression of distinct galectins in multiple sclerosis lesions.
Stancic M, van Horssen J, Thijssen VL, Gabius HJ, van der Valk P, Hoekstra D, Baron W.
Neuropathol Appl Neurobiol. 2011 Oct;37(6):654-71

Toward bioinspired galectin mimetics: identification of ligand-contacting peptides by proteolytic-excision mass spectrometry.
Moise A, André S, Eggers F, Krzeminski M, Przybylski M, Gabius HJ.
J Am Chem Soc. 2011 Sep 28;133(38):14844-7

(1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 31 kDa human galectin-7 (p53-induced gene 1) homodimer, a pro-apoptotic lectin.
Nesmelova IV, Berbís MA, Miller MC, Cañada FJ, André S, Jiménez-Barbero J, Gabius HJ, Mayo KH.
Biomol NMR Assign. 2011 Sep 7

Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression.
Wu G, Lu ZH, Gabius HJ, Ledeen RW, Bleich D.
Diabetes. 2011 Sep;60(9):2341-9

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.
Martín-Santamaría S, André S, Buzamet E, Caraballo R, Fernández-Cureses G, Morando M, Ribeiro JP, Ramírez-Gualito K, de Pascual-Teresa B, Cañada FJ, Menéndez M, Ramström O, Jiménez-Barbero J, Solís D, Gabius HJ.
Org Biomol Chem. 2011 Aug 7;9(15):5445-55

Galectins promote the interaction of influenza virus with its target cell.
Chernyy ES, Rapoport EM, André S, Kaltner H, Gabius HJ, Bovin NV.
Biochemistry (Mosc). 2011 Aug;76(8):958-67

Combining carbohydrate substitutions at bioinspired positions with multivalent presentation towards optimising lectin inhibitors: case study with calixarenes.
André S, Grandjean C, Gautier FM, Bernardi S, Sansone F, Gabius HJ, Ungaro R.
Chem Commun (Camb). 2011 Jun 7;47(21):6126-8

Galectins as tools for glycan mapping in histology: comparison of their binding profiles to the bovine zona pellucida by confocal laser scanning microscopy.
Habermann FA, André S, Kaltner H, Kübler D, Sinowatz F, Gabius HJ.
Histochem Cell Biol. 2011 Jun;135(6):539-52

Cyclic neoglycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells.
André S, Renaudet O, Bossu I, Dumy P, Gabius HJ.
J Pept Sci. 2011 Jun;17(6):427-37

From lectin structure to functional glycomics: principles of the sugar code.
Gabius HJ, André S, Jiménez-Barbero J, Romero A, Solís D.
Trends Biochem Sci. 2011 Jun;36(6):298-313

Inhibitory potential of chemical substitutions at bioinspired sites of β-D-galactopyranose on neoglycoprotein/cell surface binding of two classes of medically relevant lectins.
Giguère D, André S, Bonin MA, Bellefleur MA, Provencal A, Cloutier P, Pucci B, Roy R, Gabius HJ.
Bioorg Med Chem. 2011 May 15;19(10):3280-7

Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin.
Sanchez-Ruderisch H, Detjen KM, Welzel M, André S, Fischer C, Gabius HJ, Rosewicz S.
Cell Death Differ. 2011 May;18(5):806-16

Nitric oxide changes distinct aspects of the glycophenotype of human neuroblastoma NB69 cells.
Van de Wouwer M, André S, Gabius HJ, Villalobo A.
Nitric Oxide. 2011 Mar 15;24(2):91-101

Toward comprehensive analysis of the galectin network in chicken: unique diversity of galectin-3 and comparison of its localization profile in organs of adult animals to the other four members of this lectin family.
Kaltner H, Kübler D, López-Merino L, Lohr M, Manning JC, Lensch M, Seidler J, Lehmann WD, André S, Solís D, Gabius HJ.
Anat Rec (Hoboken). 2011 Mar;294(3):427-44

Negative regulation of RPE cell attachment by carbohydrate-dependent cell surface binding of galectin-3 and inhibition of the ERK-MAPK pathway.
Alge-Priglinger CS, André S, Schoeffl H, Kampik A, Strauss RW, Kernt M, Gabius HJ, Priglinger SG.
Biochimie. 2011 Mar;93(3):477-88

Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential.
Remmelink M, de Leval L, Decaestecker C, Duray A, Crompot E, Sirtaine N, André S, Kaltner H, Leroy X, Gabius HJ, Saussez S.
Histopathology. 2011 Mar;58(4):543-56

Human galectin-3 (Mac-2 antigen): defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region.
Krzeminski M, Singh T, André S, Lensch M, Wu AM, Bonvin AM, Gabius HJ.
Biochim Biophys Acta. 2011 Feb;1810(2):150-61

A regulatory network of two galectins mediates the earliest steps of avian limb skeletal morphogenesis.
Bhat R, Lerea KM, Peng H, Kaltner H, Gabius HJ, Newman SA.
BMC Dev Biol. 2011 Feb 1;11:6

Adhesion/growth-regulatory galectins: insights into their ligand selectivity using natural glycoproteins and glycotopes.
Wu AM, Singh T, Liu JH, André S, Lensch M, Siebert HC, Krzeminski M, Bonvin AM, Kaltner H, Wu JH, Gabius HJ.
Adv Exp Med Biol. 2011;705:117-41

Glycobiomarkers by glycoproteomics and glycan profiling (glycomics): emergence of functionality.
Gabius HJ.
Biochem Soc Trans. 2011 Jan;39(1):399-405

Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair.
Dvořánková B, Szabo P, Lacina L, Gal P, Uhrova J, Zima T, Kaltner H, André S, Gabius HJ, Sykova E, Smetana K Jr.
Cells Tissues Organs. 2011;194(6):469-80

Comparative analysis of the nuclear presence of adhesion/growth-regulatory galectins and reactivity in the nuclei of interphasic and mitotic cells.
Kodet O, Dvořánková B, Lacina L, André S, Kaltner H, Gabius HJ, Smetana K Jr.
Folia Biol (Praha). 2011;57(3):125-32