Physiologische Chemie Tiermedizin




Publications 2008

Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration.
Klíma J, Lacina L, Dvořánková B, Herrmann D, Carnwath JW, Niemann H, Kaltner H, André S, Motlík J, Gabius HJ, Smetana Jr K.
Physiol Res. 2008 Dec 17. [Epub ahead of print]

Glycans: bioactive signals decoded by lectins.
Gabius HJ.
Biochem Soc Trans. 2008 Dec;36(Pt 6):1491-6. Review.

Single-site Cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation.
Wang H, He L, Lensch M, Gabius HJ, Fee CJ, Middelberg AP.
Biomacromolecules. 2008 Nov;9(11):3223-30. Epub 2008 Oct 23.

Versatile strategy for the synthesis of biotin-labelled glycans, their immobilization to establish a bioactive surface and interaction studies with a lectin on a biochip.
Muñoz FJ, Rumbero A, Sinisterra JV, Santos JI, André S, Gabius HJ, Jiménez-Barbero J, Hernáiz MJ.
Glycoconj J. 2008 Oct;25(7):633-46. Epub 2008 Mar 18.

The application of neoglycopeptides in the development of sensitive surface plasmon resonance-based biosensors.
Maljaars CE, de Souza AC, Halkes KM, Upton PJ, Reeman SM, André S, Gabius HJ, McDonnell MB, Kamerling JP.
Biosens Bioelectron. 2008 Sep 15;24(1):60-5. Epub 2008 Mar 22.

Cell-type-specific expression of murine multifunctional galectin-3 and its association with follicular atresia/luteolysis in contrast to pro-apoptotic galectins-1 and -7.
Lohr M, Kaltner H, Lensch M, André S, Sinowatz F, Gabius HJ.
Histochem Cell Biol. 2008 Sep;130(3):567-81. Epub 2008 Jul 3.

Galectin-3 upregulation during tumor progression in head and neck cancer.
Saussez S, Decaestecker C, Mahillon V, Cludts S, Capouillez A, Chevalier D, Vet HK, André S, Toubeau G, Leroy X, Gabius HJ.
Laryngoscope. 2008 Sep;118(9):1583-90.

Assessing the inhibitory potency of galectin ligands identified from combinatorial (glyco)peptide libraries using surface plasmon resonance spectroscopy.
Maljaars CE, André S, Halkes KM, Gabius HJ, Kamerling JP.
Anal Biochem. 2008 Jul 15;378(2):190-6. Epub 2008 Apr 23.

Calix[n]arene-based glycoclusters: bioactivity of thiourea-linked galactose/lactose moieties as inhibitors of binding of medically relevant lectins to a glycoprotein and cell-surface glycoconjugates and selectivity among human adhesion/growth-regulatory galectins.
André S, Sansone F, Kaltner H, Casnati A, Kopitz J, Gabius HJ, Ungaro R.
Chembiochem. 2008 Jul 2;9(10):1649-61.

Duodenal phytohaemagglutinin (red kidney bean lectin) stimulates gallbladder contraction in humans.
Purhonen AK, Herzig KH, Gabius HJ, André S, Ketterer S, Matzinger D, Beglinger C, Hildebrand P.
Acta Physiol (Oxf). 2008 Jul;193(3):241-7. Epub 2008 Feb 1.

Serum galectin-1 and galectin-3 levels in benign and malignant nodular thyroid disease.
Saussez S, Glinoer D, Chantrain G, Pattou F, Carnaille B, André S, Gabius HJ, Laurent G.
Thyroid. 2008 Jul;18(7):705-12.

Domain versatility in plant AB-toxins: evidence for a local, pH-dependent rearrangement in the 2gamma lectin site of the mistletoe lectin by applying ligand derivatives and modelling.
Jiménez M, André S, Barillari C, Romero A, Rognan D, Gabius HJ, Solís D.
FEBS Lett. 2008 Jun 25;582(15):2309-12. Epub 2008 Jun 2.

Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy.
Kübler D, Hung CW, Dam TK, Kopitz J, André S, Kaltner H, Lohr M, Manning JC, He L, Wang H, Middelberg A, Brewer CF, Reed J, Lehmann WD, Gabius HJ.
Biochim Biophys Acta. 2008 Apr;1780(4):716-22. Epub 2008 Feb 12.

Galectin-loaded cells as a platform for the profiling of lectin specificity by fluorescent neoglycoconjugates: a case study on galectins-1 and -3 and the impact of assay setting.
Rapoport EM, André S, Kurmyshkina OV, Pochechueva TV, Severov VV, Pazynina GV, Gabius HJ, Bovin NV.
Glycobiology. 2008 Apr;18(4):315-24. Epub 2008 Feb 6.

Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas.
Saussez S, Decaestecker C, Lorfevre F, Chevalier D, Mortuaire G, Kaltner H, André S, Toubeau G, Gabius HJ, Leroy X.
Histopathology. 2008 Mar;52(4):483-93.

Human galectins as sensors for apoptosis/necrosis-associated surface changes of granulocytes and lymphocytes.
Beer A, André S, Kaltner H, Lensch M, Franz S, Sarter K, Schulze C, Gaipl US, Kern P, Herrmann M, Gabius HJ.
Cytometry A. 2008 Feb;73(2):139-47.

Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors.
Dvoránková B, Lacina L, Smetana K Jr, Lensch M, Manning JC, André S, Gabius HJ.
Histol Histopathol. 2008 Feb;23(2):167-78.

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals.
Kaltner H, Solís D, Kopitz J, Lensch M, Lohr M, Manning JC, Mürnseer M, Schnölzer M, André S, Sáiz JL, Gabius HJ.
Biochem J. 2008 Jan 15;409(2):591-9.