Physiologische Chemie Tiermedizin




Publications 2002

Galectins-1 and -3 in fetal development of bovine respiratory and digestive tracts: comparison of cell-type-specific expression profiles and subcellular localization.
H. Kaltner, K. Seyrek, A. Heck, F. Sinowatz, H.-J. Gabius
Cell Tissue Res. 307, 35-46 (2002).

Galectin-8 expression decreases in cancer as compared to normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as suppressor.
N. Nagy, Y. Bronckart, I. Camby, H. Legendre, H. Lahm, H. Kaltner, Y. R. Hadari, P. Van Ham, P. Yeaton, J.-C. Pector, Y. Zick, I. Salmon, A. Danguy, R. Kiss, H.-J. Gabius
Gut 50, 392-401 (2002).

Structure-activity profiles of complex biantennary glycans with core fucosylation and with/without additional a2,3/a2,6 sialylation: synthesis of neoglycoproteins and their properties in lectin assays, cell binding and organ uptake.
C. Unverzagt, S. André, J. Seifert, C. Fink, G. Srikrishna, H. Freeze, K. Kayser, H.-J. Gabius
J. Med. Chem. 45, 478-491 (2002).

Galectin fingerprinting by immuno- and lectin histochemistry in cutaneous lymphoma. U. Wollina, T. Graefe, S. Feldrappe, S. André, K. Wasano, H. Kaltner, Y. Zick,
H.-J. Gabius
J. Cancer Res. Clin. Oncol. 128, 103-110 (2002).

Association of galectin-1- and not galectin-3-dependent parameters with proliferation activity in human neuroblastomas and small cell lung carcinomas.
H.-J. Gabius, S. André, I. Gunsenhäuser, H. Kaltner, G. Kayser, J. Kopitz, H. Lahm, D. Harms, J. Szymas, K. Kayser
Anticancer Res. 22, 405-410 (2002).

Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration.
C. Delbrouck, I. Doyen, N. Belot, C. Decaestecker, R. Ghanooni, A. de Lavareille, H. Kaltner, G. Choufani, A. Danguy, G. Vandenhoven, H.-J. Gabius, S. Hassid, R. Kiss
Lab. Invest. 82, 147-158 (2002).

CD4+CD7- Leukemic T cells in patients with Sézary syndrome are protected from galectin-1-triggered T cell death.
G. Rappl, H. Abken, J. M. Muche, W. Sterry, W. Tilgen, S. André, H. Kaltner, S. Ugurel, H.-J. Gabius, U. Reinhold
Leukemia 16, 840-846 (2002).

Primary colorectal carcinomas and their intrapulonary metastases: clinical, glyco-, immuno-, and lectinhistochemical, nuclear and syntactic structure analysis with emphsis on correlation to period of occurrence of metastases and survival.
K. Kayser, S. Zink, S. André, M.-P. Schüring, E. Hecker, E. Klar, N. V. Bovin, H. Kaltner, H.-J. Gabius
APMIS 110, 435-446 (2002).

Glucocorticoid-induced differential expression of the sialylated/non-sialylated Lewis a and Lewis x epitopes and respective binding sites in human nasal polyps maintained under oganotypical culture conditions.
C. Delbrouck, H. Kaltner, A. Danguy, N. E. Nifant’ev, N. V. Bovin, G. Vandenhoven, H. J. Gabius, R. Kiss, S. Hassid
Ann. Otol. Rhinol. Laryngol. 111, 1097-1107 (2002).

Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and the levels of expression of small GTPases.
I. Camby, N. Belot, F. Lefrance, N. Sadeghi, Y. de Launoit, H. Kaltner, S. Musette, F. Darro, A. Danguy, I. Salmon, H.-J. Gabius, R. Kiss
J. Neuropathol. Exp. Neurol. 61, 585-596 (2002).

Animal lectins and life: A guided tour into the realm of the sugar code.
H.-J. Gabius
Biochim. Biophys. Acta, 1572, 163-164 (2002).

The Sugar Code: functional lectinomics.
H.-J. Gabius, S. André, H. Kaltner, H.-C. Siebert
Biochim. Biophys. Acta, 1572, 165-177 (2002).

Analysis of protein-carbohydrate (TF-antigen) interaction at the lower size limit of the protein part (15-mer peptide) by NMR spectroscopy, electrospray ionization mass spectrometry and molecular modeling.
H.-C. Siebert, S.-Y. Lü, M. Frank, J. Kramer, R. Wechselberger, J. Joosten, S. André, K. Rittenhouse-Olson, R. Roy, C.-W. von der Lieth, R. Kaptein, J. F. G. Vliegenthart, A. J. R. Heck, H.-J. Gabius
Biochemistry 41, 9707-9717 (2002).

Craniopharyngioma: A case report and comparative galectin histochemical analysis. Histochem.
J. Plzák, P. Haninec, K. Smetana Jr., Z. Holiková, S. André, H. Kaltner, I. Kuwabara, F.-T. Liu, H.-J. Gabius
J. 34, 117-122 (2002).

Fine specificity of the domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N).
A. M. Wu, J. H. Wu, M.-S. Tsai, J.-H. Liu, S. André, K. Wasano, H. Kaltner, H.-J. Gabius
Biochem. J. 367, 653-664 (2002).

Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implication.
S. Rorive, B. Eddafali, S. Fernandez, C. Decaestecker, S. André, H. Kaltner, I. Kuwabara, F.-T. Liu, H.-J. Gabius, R. Kiss, I. Salmon
Modern Pathol. 15, 1294-1301 (2002).

Thermodynamic binding studies of cell surface carbohydrate epitopes to galectins-1, -3, and -7. Evidence for differential binding specificities.
N. Ahmad, H.-J. Gabius, H. Kaltner, S. André, I. Kuwabara, F.-T. Liu, S. Oscarson, T. Norberg, C. F. Brewer
Can. J. Chem. 80, 1096-1104 (2002).

Galectin-1 augments Ras activation and diverts Ras signals to Raf-1 at the expense of phosphoinositide 3-kinase.
G. Elad-Sfadia, R. Haklai, E. Ballan, H.-J. Gabius, Y. Kloog
J. Biol. Chem. 277, 37169-37175 (2002).

Defining the glycophenotype of squamous epithelia by plant and mammalian lectins.
Z. Holíková, E. Hrdliková-Cela, J. Plzák, K. Smetana Jr., J. Betka, B. Dvoránková, M. Esner, K. Wasano, S. André, H. Kaltner, J. Motlík, J. Hercogová, R. Kodet, H.-J. Gabius
APMIS 110, 845-856 (2002).

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin.
J. Plzák, Z. Holiková, K. Smetana Jr., B. Dvoránková, J. Hercogová, H. Kaltner, J. Motlík, H.-J. Gabius
Cells Tissues Organs 171, 135-144 (2002).