Physiologische Chemie Tiermedizin




Publikationen 2013

Breaking pseudo-symmetry in multiantennary complex N-glycans using lanthanide-binding tags and NMR pseudo-contact shifts.
Canales A, Mallagaray A, Pérez-Castells J, Boos I, Unverzagt C, André S, Gabius HJ, Cañada FJ, Jiménez-Barbero J.
Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13789-93.

Phosphorylation of multifunctional galectins by protein kinases CK1, CK2, and PKA.
Kübler D, Seidler J, André S, Kumar S, Schwartz-Albiez R, Lehmann WD, Gabius HJ.
Anal Biochem. 2013 Dec 10;449C:109-117.

Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoprotein.
Toegel S, Bieder D, André S, Altmann F, Walzer SM, Kaltner H, Hofstaetter JG, Windhager R, Gabius HJ.
Arthritis Res Ther. 2013 Oct 4;15(5):R147.

Peptides derived from human galectin-3 N-terminal tail interact with its carbohydrate recognition domain in a phosphorylation-dependent manner.
Berbís MÁ, André S, Cañada FJ, Pipkorn R, Ippel H, Mayo KH, Kübler D, Gabius HJ, Jiménez-Barbero J.
Biochem Biophys Res Commun. 2014 Jan 3;443(1):126-31.

Conformational selection in glycomimetics: human galectin-1 only recognizes syn-Ψ-type conformations of β-1,3-linked lactose and its C-glycosyl derivative.
Vidal P, Roldós V, Fernández-Alonso Mdel C, Vauzeilles B, Bleriot Y, Cañada FJ, André S, Gabius HJ, Jiménez-Barbero J, Espinosa JF, Martín-Santamaría S.
Chemistry. 2013 Oct 18;19(43):14581-90.

Human tandem-repeat-type galectins bind bacterial non-βGal polysaccharides.
Knirel YA, Gabius HJ, Blixt O, Rapoport EM, Khasbiullina NR, Shilova NV, Bovin NV.
Glycoconj J. 2014 Jan;31(1):7-12.

Fine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlations.
Ruiz FM, Fernández IS, López-Merino L, Lagartera L, Kaltner H, Menéndez M, André S, Solís D, Gabius HJ, Romero A.
Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1665-76.

The growing galectin network in colon cancer and clinical relevance of cytoplasmic galectin-3 reactivity.
Dawson H, André S, Karamitopoulou E, Zlobec I, Gabius HJ.
Anticancer Res. 2013 Aug;33(8):3053-9.

Copy-number variation of functional galectin genes: studying animal galectin-7 (p53-induced gene 1 in man) and tandem-repeat-type galectins-4 and -9.
Kaltner H, Raschta AS, Manning JC, Gabius HJ.
Glycobiology. 2013 Oct;23(10):1152-63.

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins.
Percec V, Leowanawat P, Sun HJ, Kulikov O, Nusbaum CD, Tran TM, Bertin A, Wilson DA, Peterca M, Zhang S, Kamat NP, Vargo K, Moock D, Johnston ED, Hammer DA, Pochan DJ, Chen Y, Chabre YM, Shiao TC, Bergeron-Brlek M, André S, Roy R, Gabius HJ, Heiney PA.
J Am Chem Soc. 2013 Jun 19;135(24):9055-77.

Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells.
Kindt N, Laurent G, Nonclercq D, Journé F, Ghanem G, Duvillier H, Gabius HJ, Lechien J, Saussez S.
Int J Oncol. 2013 Jul;43(1):185-93.

Single-site mutational engineering and following monoPEGylation of the human lectin galectin-2: effects on ligand binding, functional aspects, and clearance from serum.
Kopitz J, Fik Z, André S, Smetana K Jr, Gabius HJ.
Mol Pharm. 2013 May 6;10(5):2054-61.

The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity.
Murphy PV, André S, Gabius HJ.
Molecules. 2013 Apr 4;18(4):4026-53.

Fluorinated carbohydrates as lectin ligands: dissecting glycan-cyanovirin interactions by using 19F NMR spectroscopy.
Matei E, André S, Glinschert A, Infantino AS, Oscarson S, Gabius HJ, Gronenborn AM.
Chemistry. 2013 Apr 22;19(17):5364-74.

Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive cooperativity.
Ermakova E, Miller MC, Nesmelova IV, López-Merino L, Berbís MA, Nesmelov Y, Tkachev YV, Lagartera L, Daragan VA, André S, Cañada FJ, Jiménez-Barbero J, Solís D, Gabius HJ, Mayo KH.
Glycobiology. 2013 May;23(5):508-23.

Molecular recognition of complex-type biantennary N-glycans by protein receptors: a three-dimensional view on epitope selection by NMR.
Ardá A, Blasco P, Varón Silva D, Schubert V, André S, Bruix M, Cañada FJ, Gabius HJ, Unverzagt C, Jiménez-Barbero J.
J Am Chem Soc. 2013 Feb 20;135(7):2667-75.

Macrophage migration inhibitory factor in head and neck squamous cell carcinoma: clinical and experimental studies.
Kindt N, Preillon J, Kaltner H, Gabius HJ, Chevalier D, Rodriguez A, Johnson BD, Megalizzi V, Decaestecker C, Laurent G, Saussez S.
J Cancer Res Clin Oncol. 2013 May;139(5):727-37.

Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.
Velasco S, Díez-Revuelta N, Hernández-Iglesias T, Kaltner H, André S, Gabius HJ, Abad-Rodríguez J.
J Neurochem. 2013 Apr;125(1):49-62.

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target.
Smetana K Jr, André S, Kaltner H, Kopitz J, Gabius HJ.
Expert Opin Ther Targets. 2013 Apr;17(4):379-92.

Targeting matrix metalloproteinases: design of a bifunctional inhibitor for presentation by tumour-associated galectins.
Bartoloni M, Domínguez BE, Dragoni E, Richichi B, Fragai M, André S, Gabius HJ, Ardá A, Luchinat C, Jiménez-Barbero J, Nativi C.
Chemistry. 2013 Feb 4;19(6):1896-902.

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
Sarter K, Janko C, André S, Muñoz LE, Schorn C, Winkler S, Rech J, Kaltner H, Lorenz HM, Schiller M, Andreoli L, Manfredi AA, Isenberg DA, Schett G, Herrmann M, Gabius HJ.
Glycobiology. 2013 Jan;23(1):12-22.

Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas.
Fík Z, Valach J, Chovanec M, Mazánek J, Kodet R, Kodet O, Tachezy R, Foltynová E, André S, Kaltner H, Gabius HJ, Smetana K Jr.
J Oral Pathol Med. 2013 Feb;42(2):166-73.