Physiologische Chemie Tiermedizin




Publikationen 2010

Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.
Sanchez-Ruderisch H, Fischer C, Detjen KM, Welzel M, Wimmel A, Manning JC, André S, Gabius HJ.
FEBS J. 2010 Sep;277(17):3552-63

A novel galectin-1 and interleukin 2 receptor beta haplotype is associated with autoimmune myasthenia gravis.
Pál Z, Antal P, Millinghoffer A, Hullám G, Pálóczi K, Tóth S, Gabius HJ, Molnár MJ, Falus A, Buzás EI.
J Neuroimmunol. 2010 Aug 20

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane.
Kopitz J, Bergmann M, Gabius HJ.
IUBMB Life. 2010 Aug;62(8):624-8

Towards Functional Glycomics by Lectin Histochemistry: Strategic Probe Selection to Monitor Core and Branch-end Substitutions and Detection of Cell-type and Regional Selectivity in Adult Mouse Testis and Epididymis.
Lohr M, Kaltner H, Schwartz-Albiez R, Sinowatz F, Gabius HJ.
Anat Histol Embryol. 2010 Jul 7

Binding studies of adhesion/growth-regulatory galectins with glycoconjugates monitored by surface plasmon resonance and NMR spectroscopy.
Muñoz FJ, Santos JI, Ardá A, André S, Gabius HJ, Sinisterra JV, Jiménez-Barbero J, Hernáiz MJ.
Org Biomol Chem. 2010 Jun 28;8(13):2986-92

Hydrodynamic properties of human adhesion/growth-regulatory galectins studied by fluorescence correlation spectroscopy.
Göhler A, André S, Kaltner H, Sauer M, Gabius HJ, Doose S.
Biophys J. 2010 Jun 16;98(12):3044-53

N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution.
Solís D, Maté MJ, Lohr M, Ribeiro JP, López-Merino L, André S, Buzamet E, Cañada FJ, Kaltner H, Lensch M, Ruiz FM, Haroske G, Wollina U, Kloor M, Kopitz J, Sáiz JL, Menéndez M, Jiménez-Barbero J, Romero A, Gabius HJ.
Int J Biochem Cell Biol. 2010 Jun;42(6):1019-29

Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes.
Belisle JA, Horibata S, Jennifer GA, Petrie S, Kapur A, André S, Gabius HJ, Rancourt C, Connor J, Paulson JC, Patankar MS.
Mol Cancer. 2010 May 24;9:118

Galectin fingerprinting in Warthin's tumors: lectin-based approach to trace its origin?
Saussez S, de Leval L, Decaestecker C, Sirtaine N, Cludts S, Duray A, Chevalier D, André S, Gabius HJ, Remmelink M, Leroy X.
Histol Histopathol. 2010 May;25(5):541-50

Solid-phase assays for study of carbohydrate specificity of galectins.
Rapoport EM, Pochechueva TV, Kurmyshkina OV, Pazynina GV, Severov VV, Gordeeva EA, Belyanchikov IM, André S, Gabius HJ, Bovin NV.
Biochemistry (Mosc). 2010 Mar;75(3):310-9

The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic cleavage.
Ulmer TA, Keeler V, André S, Gabius HJ, Loh L, Laferté S.
Biochim Biophys Acta. 2010 Mar;1800(3):336-43

Lectin-based drug design: combined strategy to identify lead compounds using STD NMR spectroscopy, solid-phase assays and cell binding for a plant toxin model.
Ribeiro JP, André S, Cañada FJ, Gabius HJ, Butera AP, Alves RJ, Jiménez-Barbero J.
ChemMedChem. 2010 Mar 1;5(3):415-9, 314

Phosphorylation of adhesion- and growth-regulatory human galectin-3 leads to the induction of axonal branching by local membrane L1 and ERM redistribution.
Díez-Revuelta N, Velasco S, André S, Kaltner H, Kübler D, Gabius HJ, Abad-Rodríguez J.
J Cell Sci. 2010 Mar 1;123(Pt 5):671-81

Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages.
Barrès C, Blanc L, Bette-Bobillo P, André S, Mamoun R, Gabius HJ, Vidal M.
Blood. 2010 Jan 21;115(3):696-705

Diffusion nuclear magnetic resonance spectroscopy detects substoichiometric concentrations of small molecules in protein samples.
Ribeiro JP, Palczewska M, André S, Cañada FJ, Gabius HJ, Jiménez-Barbero J, Mellström B, Naranjo JR, Scheffers DJ, Groves P.
Anal Biochem. 2010 Jan 1;396(1):117-23