Physiologische Chemie Tiermedizin




Publikationen 2005

Detection of new diagnostic markers in pathology by focus on growth-regulatory endogenous lectins. The case study of galectin-7 in squamous epithelia.
M. Chovanec, K. Jr. Smetana, J. Plzak, J. Betka, Z. Plzakova, J. Stork, E. Hrdlickova, I. Kuwabara, B. Dvorankova, F.-T. Liu, H. Kaltner, S. André, H.-J. Gabius HJ
Prague Med. Rep. 106, 209-216 (2005).

Localized fibrous tumors (LFTs) of the pleura: Clinical data, asbestos burden, and syntactic structure analysis applied to newly defined angiogenic/growth-regulatory effectors.
K. Kayser, J. Trott, G. Bohm, M. Huber, H. Kaltner, S. André, H.-J. Gabius
Pathol. Res. Pract. 201, 791-801 (2005).

The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acida2,6GalNAc.
E. I. Park, Y. Mi, C. Unverzagt, H.-J. Gabius, J. U.Baenziger
Proc. Natl. Acad. Sci. U S A. 102, 17125-17129 (2005).

Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.
K. Jr. Smetana, B. Dvorankova, M. Chovanec, J. Boucek, J. Klima, J. Motlik, M. Lensch, H. Kaltner, S. André, H.-J. Gabius HJ
Histochem. Cell Biol., 1-12 (2005).

Regulation of expression of galectin-7 in human nasal polyps by budesonide.
C. Delbrouck, C. Souchay, H. Kaltner, S. André, H.-J. Gabius, G. Vandenhoven, S. Hassid
B-ENT 1, 137-144 (2005).

Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants.
T. K. Dam, H.-J. Gabius, S. André, H. Kaltner, M. Lensch, C. F. Brewer
Biochemistry 44, 12564-12571 (2005).

Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells.
B. Dvorankova, K. Jr. Smetana, M. Chovanec, L. Lacina, J. Stork, Z. Plzakova, M. Galovicova, H.-J. Gabius
Int. J. Mol. Med. 16, 525-531 (2005).

Human galectin-2: expression profiling by RT-PCR/immunohistochemistry and its introduction as a histochemical tool for ligand localization.
I. Saal, N. Nagy, M. Lensch, M. Lohr, J. C. Manning, C. Decaestecker, S. André, R. Kiss, I. Salmon, H.-J. Gabius
Histol. Histopathol. 20, 1191-1208 (2005).

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer.
T. Szoke, K. Kayser, J. D. Baumhäkel, I. Trojan, J. Furak, L. Tiszlavicz, A. Horvath, K. Szluha, H.-J. Gabius, S. André
Oncology 69, 167-174 (2005).

Galectin-1 interacts with the a5b1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27.
C. Fischer, H. Sanchez-Ruderisch, M. Welzel, B. Wiedenmann, T. Sakai, S. André, H.-J. Gabius, L. Khachigian, K. M. Detjen, S. Rosewicz
J. Biol. Chem. 280, 37266-37277 (2005).

Galectin-1 knocking down in human U87 glioblastoma cells alters their gene expression pattern.
I. Camby, C. Decaestecker, F. Lefranc, H. Kaltner, H.-J. Gabius, R. Kiss
Biochem. Biophys. Res. Commun. 335, 27-35 (2005).

Monomer/dimer equilibrium of the AB-type lectin from mistletoe enables combination of toxin/agglutinin activities in one protein: analysis of native and citraconylated proteins by ultracentrifugation/gel filtration and cell biological consequences of dimer destabilization.
M. Jimenez, J. L. Saiz, S. André, H.-J. Gabius, D. Solis
Glycobiology 15, 1386-1395 (2005).

Correlation of expression of nuclear proteins pKi67 and p63 with lectin histochemical features in head and neck squamous cell cancer.
M. Chovanec, K. Jr. Smetana, J. Betka, J. Plzak, J. Brabec, V. Moya-Alvarez, S. André, R. Kodet, H.-J. Gabius
Int. J. Oncol. 27, 409-415 (2005).

Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells.
D. Delacour, V. Gouyer, J. P. Zanetta, H. Drobecq, E. Leteurtre, G. Grard, O. Moreau-Hannedouche, E. Maes, A. Pons, S. André, A. Le Bivic, H.-J. Gabius, A. Manninen, K. Simons, G. Huet
J. Cell. Biol. 169, 491-501 (2005).

Evidence for lectin activity of a plant receptor-like protein kinase by application of neoglycoproteins and bioinformatic algorithms.
S. André, H.-J. Siebert, M. Nishiguchi, K. Tazaki, H.-J. Gabius
Biochim. Biophys. Acta. 1725, 222-232 (2005).

Nuclear galectin-3 expression is an independent predictive factor of recurrence for adenocarcinoma and squamous cell carcinoma of the lung.
A. Mathieu, I. Saal, A. Vuckovic, V. Ransy, P. Vereerstraten, H. Kaltner, H.-J. Gabius, R. Kiss, C. Decaestecker, I. Salmon, M. Remmelink
Mod. Pathol. 18, 1264-1271 (2005).

Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan.
S. André, S. Kojima, I. Prahl, M. Lensch, C. Unverzagt, H.-J. Gabius
FEBS J. 272, 1986.1998 (2005).

Toward functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster.
S. Saussez, D. Nonclercq, G. Laurent, R. Wattiez, S. André, H. Kaltner, H.-J. Gabius, R. Kiss, G. Toubeau G
Histochem. Cell. Biol. 123, 29-41 (2005).

Monitoring the expression profiles of integrins and adhesion/growth-regulatory galectins in adamantinomatous craniopharyngiomas: Their ability to regulate tumor adhesiveness to surrounding tissue and their contribution to prognosis.
F. Lefranc, T. Mijatovic, C. Decaestecker, H. Kaltner, S. André, J. Brotchi, I. Salmon, H.-J. Gabius, R. Kiss
Neurosurgery 56, 763-776 (2005).

Comparative phenotypic characterization of keratinocytes originating from hair follicles.
J. Klima, K. Jr. Smetana, J. Motlik, Z. Plzakova, F.-T. Liu, J. Stork, H. Kaltner, M. Chovanec, B. Dvorankova, S. André, H.-J. Gabius
J. Mol. Histol.. 36, 89-96 (2005).

Galectin fingerprinting in human endometrium and decidua during the menstrual cycle and in early gestation.
M. von Wolff, X. Wang, H.-J. Gabius, T. Strowitzki
Mol. Hum. Reprod. 11, 189-194 (2005).

Identification of peptide ligands for malignancy- and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries.
S. André, C. J. Arnusch, I. Kuwabara, R. Russwurm, H. Kaltner, H.-J. Gabius, R. J. Pieters.
Bioorg. Med. Chem. 13, 563-573 (2005).

Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells.
S. André, H. Kaltner, M. Lensch, R. Russwurm, H.-C. Siebert, C. Fallsehr, E. Tajkhorshid, A. J. Heck, M. von Knebel Doeberitz, H.-J. Gabius, J. Kopitz.
Int. J. Cancer. 114, 46-57 (2005).